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Collectively, PCBPs can regulate the cellular distribution of labile iron by depositing it into the cellular iron reservoir ferritin and/or by directing it to the site of utilization as an inorganic cofactor for cytosolic non-heme iron enzymes

Highlights An FDA panel voted eight to six to end prohibitions on BPC-157, despite agency staff concerns about insufficient scientific evidence and regulatory clarity

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3.5 Traumatic brain injury Studies on traumatic brain injury (TBI) in both humans and animals have shown an acute increase in tissue glutamate concentrations that persist at elevated levels for up to 5 days in humans

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According to the applicant, it anticipates BLA approval from FDA for the treatment of patients with hematologic malignancies in need of a hematopoietic stem cell transplant before July 1, 2023